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12/17/2021
On Frequentist and Bayesian Sequential Clinical Trial Designs
Clinical trials usually involve sequential patient entry. When designing...
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07/21/2021
Tracking the Transmission Dynamics of COVID-19 with a Time-Varying Coefficient State-Space Model
The spread of COVID-19 has been greatly impacted by regulatory policies ...
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03/25/2021
The Ci3+3 Design for Dual-Agent Combination Dose-Finding Clinical Trials
We propose a rule-based statistical design for combination dose-finding ...
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03/15/2021
Incorporating External Data into the Analysis of Clinical Trials via Bayesian Additive Regression Trees
Most clinical trials involve the comparison of a new treatment to a cont...
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06/20/2020
A Unified Framework for Time-to-Event Dose-Finding Designs
In dose-finding trials, due to staggered enrollment, it might be desirab...
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06/14/2020
MUCE: Bayesian Hierarchical Modeling for the Design and Analysis of Phase 1b Multiple Expansion Cohort Trials
We propose a multiple cohort expansion (MUCE) approach as a design or an...
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06/10/2020
Semiparametric Bayesian Inference for the Transmission Dynamics of COVID-19 with a State-Space Model
The outbreak of Coronavirus Disease 2019 (COVID-19) is an ongoing pandem...
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09/19/2019
Posterior Contraction Rate of Sparse Latent Feature Models with Application to Proteomics
The Indian buffet process (IBP) and phylogenetic Indian buffet process (...
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04/29/2019
PoD-TPI: Probability-of-Decision Toxicity Probability Interval Design to Accelerate Phase I Trials
Cohort-based enrollment can slow down dose-finding trials since the outc...
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10/26/2017
