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09/05/2023
Beyond the classical type I error: Bayesian metrics for Bayesian designs using informative priors
There is growing interest in Bayesian clinical trial designs with inform...
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06/27/2023
On fixed and uncertain mixture prior weights
This paper focuses on the specification of the weights for the component...
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12/20/2021
The Predictive Individual Effect for Survival Data
The call for patient-focused drug development is loud and clear, as expr...
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08/21/2019
Beyond p-values: a phase II dual-criterion design with statistical significance and clinical relevance
Background: Well-designed phase II trials must have acceptable error rat...
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08/20/2019
Bayesian leveraging of historical control data for a clinical trial with time-to-event endpoint
The recent 21st Century Cures Act propagates innovations to accelerate t...
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07/09/2019
